Medicine
* Massive Transfusion Protocol
* Medial tibial plateau, at the upper end of the tibia
* Medical termination of pregnancy, the termination of a pregnancy by the removal or expulsion of an embryo or fetus from the uterus
* Metatarsophalangeal joint, the joint between the foot and the toe
* Methadone treatment program, a form of treatment for heroin addiction
* Microsomal triglyceride transfer protein, a liver protein linked to LDL release
* Mitochondrial trifunctional protein, a protein which catalyzes several reactions in beta oxidation
Computing and Networking
* Mail Transfer Protocol, an obsolete network protocol that has been replaced by SMTP
* Media Transfer Protocol, a Microsoft protocol for transferring images, music etc. between a computer and a portable device
* Message Transfer Part, part of Signaling System 7 (SS7) used for communication in Public Switched Telephone Networks (PSTN)
* Move to Production, a term used in software development for the completion of the work and release to end users
* Multiple Time Programmable, an electronic memory cell chip containing programmable memory which is writable multiple times
* Multipurpose Transaction Protocol, a proprietary data transport protocol produced by Data Expedition, Inc.
* Message Transport Protocol, protocol for transferring FIPA-ACL messages between intelligent agents, used in Message Transport Service - MTS
* "Multi-fiber Termination Push-on" (MTP) A type of fiber cable terminator Optical fiber connector